Amycretin, Novo Nordisk’s oral GLP-1/amylin agonist, hits 13% weight loss in 12 weeks (Obesity, 2023), in Phase II with Phase III eyed late 2025. At SeraVia Health, GLP Energy+ Boost and GLP Gut+ Balance support your Amycretin journey. Let’s explore what it is, its pros and cons, how it differs, and how our products enhance it, with science as our twist.
What Is Amycretin?
Amycretin is a once-daily oral GLP-1/amylin agonist in Phase II, targeting obesity and diabetes. GLP-1 curbs appetite, amylin boosts satiety (Diabetes Care, 2023). Phase I hit 13% loss—strong for oral—aiming for 2026-2027 approval with high tolerability (80% retention).
Pros of Amycretin
- Oral Power: 13% in 12 weeks—no needles (Obesity, 2023).
- Dual Action: GLP-1/amylin doubles satiety (Journal of Clinical Endocrinology & Metabolism, 2023).
- Tolerable: 80% stick with it—gentler start.
- Daily Ease: Pill fits routines.
Cons and Possible Side Effects
- Nausea: 30% report it—dual gut hit (Obesity, 2023).
- Lower Peak: 13% vs. 17-20% injectables (JAMA, 2021).
- Fatigue: 20% feel drained—calorie cuts.
- Phase II: Early—potency TBD.
How Amycretin Differs from Current GLP-1s
Unlike Rybelsus (8-9%, oral GLP-1, Diabetes Care, 2020), Amycretin’s 13% and amylin twist outpace—more satiety.
Compared to Wegovy (17.4%, JAMA, 2021), it’s oral but less potent.
Versus CagriSema (20-25%, injectable, New England Journal of Medicine, 2023), Amycretin’s oral form trades some loss for ease.
SeraVia Health’s Support for Your Amycretin Journey
Amycretin’s oral twist—our products turn it:
- GLP Energy+ Boost: 300 mg NAD+ lifts energy (Mitochondrion, 2020).
- GLP Gut+ Balance: 500 mg ginger eases nausea (Journal of Gastroenterology, 2017).
Add GLP Vitality+ Multi for nutrients.
Twist to Win
Amycretin’s oral future—win with GLP Energy+ Boost. Shop now at SeraVia Health and twist your GLP-1 success!


